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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3AP All Species: 13.03
Human Site: S993 Identified Species: 28.67
UniProt: O60318 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60318 NP_003897.2 1980 218405 S993 Q N K Y I G E S L A A E L P V
Chimpanzee Pan troglodytes XP_525497 1981 218320 S993 Q N K Y I G E S L A A E L P V
Rhesus Macaque Macaca mulatta XP_001118009 1415 157213 V573 T R K L T V S V G E V V N G G
Dog Lupus familis XP_537925 1989 218752 S993 Q N K Y I G E S L A A E L S V
Cat Felis silvestris
Mouse Mus musculus Q9WUU9 1971 217122 S986 Q N K Y V G E S L A T E L P I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514089 1519 168947 E676 V L R Q T T A E E M S Q E R E
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689234 2082 230356 G1045 N N K Y T G D G L S S E P P P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3V9 1370 158161 L527 K L P R Q Y E L V E V K R V K
Honey Bee Apis mellifera XP_395462 961 111706 I119 K I N P E N S I T C T N V P Q
Nematode Worm Caenorhab. elegans NP_501328 1116 129063 L274 F V K R D G F L C Q L R E I N
Sea Urchin Strong. purpuratus XP_795787 1945 218422 I1018 S P K V I A E I I D E E L G A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 69.1 83.7 N.A. 78.4 N.A. N.A. 53.8 N.A. N.A. 42.2 N.A. 21.3 20.6 21.3 25.4
Protein Similarity: 100 99.6 70.1 89.4 N.A. 85.5 N.A. N.A. 62.7 N.A. N.A. 58.5 N.A. 35.7 34.3 35.9 43
P-Site Identity: 100 100 6.6 93.3 N.A. 80 N.A. N.A. 0 N.A. N.A. 46.6 N.A. 6.6 6.6 13.3 33.3
P-Site Similarity: 100 100 6.6 93.3 N.A. 93.3 N.A. N.A. 20 N.A. N.A. 66.6 N.A. 26.6 20 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 0 37 28 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 10 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 10 0 55 10 10 19 10 55 19 0 10 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 55 0 10 10 0 0 0 0 19 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 37 0 0 19 10 0 0 0 0 10 10 % I
% Lys: 19 0 73 0 0 0 0 0 0 0 0 10 0 0 10 % K
% Leu: 0 19 0 10 0 0 0 19 46 0 10 0 46 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 46 10 0 0 10 0 0 0 0 0 10 10 0 10 % N
% Pro: 0 10 10 10 0 0 0 0 0 0 0 0 10 46 10 % P
% Gln: 37 0 0 10 10 0 0 0 0 10 0 10 0 0 10 % Q
% Arg: 0 10 10 19 0 0 0 0 0 0 0 10 10 10 0 % R
% Ser: 10 0 0 0 0 0 19 37 0 10 19 0 0 10 0 % S
% Thr: 10 0 0 0 28 10 0 0 10 0 19 0 0 0 0 % T
% Val: 10 10 0 10 10 10 0 10 10 0 19 10 10 10 28 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 46 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _